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. 2019 Mar 12;43(5):2133–2143. doi: 10.3892/ijmm.2019.4131

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effects of MRF on ISO-induced myocardial injury in vivo. (A) The effects of MRF on the levels of serum cardiac enzymes (CK, AST and LDH). (B) The effects of MRF on the activities of MDA, SOD and CAT in myocardial homogenates in rats. (C) The effects of MRF on the pathological alterations in rat hearts as indicated by hematoxylin and eosin staining (magnification, x200). Data (n=10 per group) are expressed as the mean ± standard deviation. ^#P<0.05, ##P<0.01 and ^###P<0.001 vs. the control group; ^*P<0.05, ^**P<0.01 and ^***P<0.001 vs. the ISO group. MRF, Myrica rubra flavonoids; Di-ao, Di-ao-xin-xue-kang capsule; ISO, isoproterenol; CK, creatine kinase; AST, aspartate aminotransferase; LDH: Lactate dehydrogenase; MDA, malondialdehyde SOD, superoxide dismutase; CAT, catalase.