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H2S upregulates LDLR expression in HepG2 cells in a concentration-dependent manner. HepG2 cells were incubated with various concentrations of NaHS (0, 50, 100 and 200 µmol/l) for 24 h. (A and B) LDLR expression was detected by western blot analysis (*P<0.05 and **P<0.01 vs. the 0 µmol/l NaHS group) (n=3). H2S, hydrogen sulfide; NaHS, sodium hydrosulfide; LDLR, low-density lipoprotein receptor.
