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The mechanisms underlying the regulation of PCSK9 expression by H2S. Effects of incubation with various concentrations of NaHS for 24 h on the expression of SREBPs in HepG2 cells. (A-C) The protein levels of SREBPs were detected by western blot analysis (*P<0.05 and **P<0.01 vs. the 0 µmol/l NaHS group) (n=3). PCSK9, proprotein convertase subtilisin/kexin type 9; NaHS, sodium hydrosulfide; SREBPs, sterol regulatory element-binding proteins.
