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. Author manuscript; available in PMC: 2019 Sep 13.
Published in final edited form as: J Med Chem. 2018 Aug 24;61(17):7700–7709. doi: 10.1021/acs.jmedchem.8b00669

Figure 5.

Figure 5.

(A) The chemical structure of AZD5438 and its EC50 in cochlear explants treated with cisplatin. (B) The dose-response and morphology of P3 cochlear explants of mice treated with AZD5438 and cisplatin. OHC counts for media alone were considered as complete protection from cisplatin-induced toxicity and OHC counts for cisplatin alone were considered as no protection.