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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: DNA Repair (Amst). 2019 Feb 6;76:40–49. doi: 10.1016/j.dnarep.2019.02.004

Figure 5. TLS DNA polymerases cooperate and serve redundant functions in microhomology mediated repair.

Figure 5.

The median frequency of MHMR, ± 95% CI, was determined for wild type (WT), single mutants of each non-essential DNA polymerase (pol4Δ, rev1Δ, rev3Δ, and rad30Δ), select double (pol4Δ rev1Δ, pol4Δ rev3Δ, and pol4Δ rad30Δ) and triple mutants (pol4Δ rev1Δ rad30Δ), and quadruple mutant (pol4Δ rev1Δ rev3Δ rad30Δ) cells. A minimum of 15 independent cultures, which possess the his3Δ3’ and his3Δ5’ mutant alleles on ectopic chromosomes sharing 14-2-4 bp of microhomolgy were examined.