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. Author manuscript; available in PMC: 2020 Apr 2.
Published in final edited form as: Circulation. 2019 Apr 2;139(14):1688–1697. doi: 10.1161/CIRCULATIONAHA.118.036553

Table 3.

Hazard ratios (95% CI) for sudden cardiac death comparing African Americans with Whites.*

Overall Women Men
AAs Whites AAs Whites AAs Whites

Events/p-y 215 / 76,344 332 / 240,514 111 / 48,983 89 / 131,436 104 / 27,361 243 / 109,078
IR per 1,000 p-y 2.8 (2.5, 3.2) 1.4 (1.2, 1.5) 2.3 (1.9, 2.7) 0.7 (0.6, 0.8) 3.8 (3.1, 4.6) 2.2 (2.0, 2.5)
Model 1 2.12 (1.79, 2.51) Ref (1) 3.25 (2.46, 4.29) Ref (1) 1.60 (1.27, 2.02) Ref (1)
Model 2 1.29 (1.06, 1.57) Ref (1) 2.06 (1.53, 2.77) Ref (1) 0.95 (0.74, 1.23) Ref (1)
Model 3§ 1.34 (1.08, 1.65) Ref (1) 1.91 (1.40, 2.61) Ref (1) 1.06 (0.81, 1.38) Ref (1)
Model 4 1.38 (1.11, 1.71) Ref (1) 1.91 (1.39, 2.62) Ref (1) 1.10 (0.84, 1.45) Ref (1)
*

Results derived from competing risk analysis using time-varying covariates.

Model 1: Adjusted for sex (women or men).

Model 2: Additionally adjusted for education (<high School, high School, or >high school), insurance (no or yes), annual household income (<16000, 16000–< 25000, 25000–<35000, 35000–<50000, or >50000), smoking status (never, former, or current), alcohol intake (non-current or current) and physical activity (continuous).

§

Model 3: Additionally adjusted for body mass index (continuous), systolic blood pressure (continuous), anti-hypertensive medication use (no or yes), diabetes, total cholesterol (continuous), HDL-cholesterol (continuous), use of lipid lowering medications (no or yes), estimated GFR (continuous), and heart rhythm medication use (no or yes).

Model 4: Additionally adjusted for heart rate (continuous), QT interval (continuous), QRS duration (continuous), LV hypertrophy (no or yes), and prevalent CHD (no or yes).

AA: African American; p-y: person-years; IR: incidence rate.