Table 3.
Hazard ratios (95% CI) for sudden cardiac death comparing African Americans with Whites.*
| Overall | Women | Men | ||||
|---|---|---|---|---|---|---|
| AAs | Whites | AAs | Whites | AAs | Whites | |
| Events/p-y | 215 / 76,344 | 332 / 240,514 | 111 / 48,983 | 89 / 131,436 | 104 / 27,361 | 243 / 109,078 |
| IR per 1,000 p-y | 2.8 (2.5, 3.2) | 1.4 (1.2, 1.5) | 2.3 (1.9, 2.7) | 0.7 (0.6, 0.8) | 3.8 (3.1, 4.6) | 2.2 (2.0, 2.5) |
| Model 1† | 2.12 (1.79, 2.51) | Ref (1) | 3.25 (2.46, 4.29) | Ref (1) | 1.60 (1.27, 2.02) | Ref (1) |
| Model 2‡ | 1.29 (1.06, 1.57) | Ref (1) | 2.06 (1.53, 2.77) | Ref (1) | 0.95 (0.74, 1.23) | Ref (1) |
| Model 3§ | 1.34 (1.08, 1.65) | Ref (1) | 1.91 (1.40, 2.61) | Ref (1) | 1.06 (0.81, 1.38) | Ref (1) |
| Model 4‖ | 1.38 (1.11, 1.71) | Ref (1) | 1.91 (1.39, 2.62) | Ref (1) | 1.10 (0.84, 1.45) | Ref (1) |
Results derived from competing risk analysis using time-varying covariates.
Model 1: Adjusted for sex (women or men).
Model 2: Additionally adjusted for education (<high School, high School, or >high school), insurance (no or yes), annual household income (<16000, 16000–< 25000, 25000–<35000, 35000–<50000, or >50000), smoking status (never, former, or current), alcohol intake (non-current or current) and physical activity (continuous).
Model 3: Additionally adjusted for body mass index (continuous), systolic blood pressure (continuous), anti-hypertensive medication use (no or yes), diabetes, total cholesterol (continuous), HDL-cholesterol (continuous), use of lipid lowering medications (no or yes), estimated GFR (continuous), and heart rhythm medication use (no or yes).
Model 4: Additionally adjusted for heart rate (continuous), QT interval (continuous), QRS duration (continuous), LV hypertrophy (no or yes), and prevalent CHD (no or yes).
AA: African American; p-y: person-years; IR: incidence rate.