Table 1.
Characteristics of study participants
| Characteristics | Probands | Participating family members | |
|---|---|---|---|
| Participants | Carriers | Noncarriers | |
| N | 21 | 20 | 44 |
| Age (years) | 47.7 (15.9) | 47.3 (17.5) | 46.25 (17.11) |
| Women | 9 (43%) | 9 (45%) | 22 (50%) |
| Blood pressure (mmHg) | |||
| Systolic | 132.4 (25.0) | 135.2 (19.2) | 137.6 (22.1) |
| Diastolic | 82. 9 (10.2) | 84.8 (12.1) | 84.5 (11.3) |
| LDL-C (mmol/L) | 5.3 (2.1) | 5.1 (1.8) | 3.4 (0.9) |
| TC (mmol/L) | 7.3 (2.2) | 6.8 (1.9) | 5.2 (0.9) |
| HDL-C (mmol/L) | 1.9 (0.8) | 1.6 (0.4) | 1.7 (0.4) |
| TG (mmol/L) | 1.2 (0.7) | 1.4 (0.9) | 1.1 (0.7) |
| Diabetes mellitus | 0 (0%) | 1 (5%) | 3 (7%) |
| Hypercholesterolemia | 13 (62%) | 8 (40%) | 3 (7%) |
| FH | 3 (14%) | 0 (0%) | 0 (0%) |
| Prevalent ASCVD | 2 (10%) | 2 (10%) | 6 (14%) |
| Body mass index | 26.5 (9.2) | 27.8 (5.7) | 27.3 (5.3) |
| Current smokers | 7 (33%) | 4 (20%) | 13 (30%) |
| Lipid-lowering medication prescription | 13 (62%) | 6 (30%) | 8 (18%) |
| Lipid-lowering medication use | 8 (38%) | 5 (25%) | 9 (20%) |
| Antihypertensive medication use | 4 (19%) | 6 (30%) | 13 (30%) |
Data are number (%) or mean (SD).
ASCVD atherosclerotic cardiovascular disease, FH familial hypercholesterolemia, HDL high-density lipoprotein, LDL low-density lipoprotein, TC total cholesterol, TG triglycerides.