Table 3:
Risks of ischemic placental disease in fresh and frozen embryo transfer cycles
| Full cohort | Singletons Only | |||
|---|---|---|---|---|
| Frozen transfers n=271 |
Fresh transfers n=1861 |
Frozen transfers n=212 |
Fresh transfers n=1251 |
|
| Small for gestational age < 10th percentile | ||||
| Ischemic placental disease or IUFD | 56 (20.7) | 512 (27.5) | 25 (11.8) | 196 (15.7) |
| Crude RR (95% CI) | 0.75 (0.59-0.96) | 1.0 | 0.75 (0.50-1.1) | 1.0 |
| Adjusted RR (95% CI)a | 0.72 (0.56-0.93) | 1.0 | 0.70 (0.46-1.1) | 1.0 |
| Preeclampsia | 27 (10.0) | 153 (8.2) | 13 (6.1) | 54 (4.3) |
| Crude RR (95% CI) | 1.2 (0.81-1.8) | 1.0 | 1.4 (0.76-2.6) | 1.0 |
| Adjusted RR (95% CI)b | 1.3 (0.84-1.9) | 1.0 | 1.5 (0.78-2.7) | 1.0 |
| Placental abruption | 8 (3.0) | 61 (3.3) | 4 (1.9) | 36 (2.9) |
| Crude RR (95% CI) | 0.90 (0.44-1.8) | 1.0 | 0.66 (0.24-1.8) | 1.0 |
| Adjusted RR (95% CI)a | 1.2 (0.56-2.4) | 1.0 | 0.79 (0.29-2.2) | 1.0 |
| Small for gestational age | 31 (11.4) | 367 (19.7) | 11 (5.2) | 127 (10.2) |
| Crude RR (95% CI) | 0.58 (0.41-0.82) | 1.0 | 0.51 (0.28-0.93) | 1.0 |
| Adjusted RR (95% CI)b | 0.58 (0.41-0.81) | 1.0 | 0.50 (0.28-0.90) | 1.0 |
| Small for gestational age < 3rd percentile | ||||
| Ischemic placental disease or IUFD | 39 (14.4) | 303 (16.3) | 17 (8.0) | 115 (9.2) |
| Crude RR (95% CI) | 0.88 (0.65-1.2) | 1.0 | 0.87 (0.53-1.4) | 1.0 |
| Adjusted RR (95% CI)b | 0.89 (0.65-1.2) | 1.0 | 0.87 (0.52-1.5) | 1.0 |
| Small for gestational age | 6 (2.2) | 112 (6.0) | 1 (0.5) | 30 (2.4) |
| Crude RR (95% CI) | 0.37 (0.16-0.83) | 1.0 | 0.20 (0.03-1.4) | 1.0 |
| Adjusted RR (95% CI)b | 0.36 (0.16-0.79) | 1.0 | 0.17 (0.02-1.3) | 1.0 |
IUFD: intrauterine fetal demise
Data presented as n (%) or risk ratio (RR) and 95% confidence interval (CI)
a
Adjusted for maternal age and year of delivery
b
Adjusted for maternal age