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. Author manuscript; available in PMC: 2019 May 3.
Published in final edited form as: Leukemia. 2018 Oct 1;33(5):1135–1147. doi: 10.1038/s41375-018-0269-8

Figure 1: Long-term tumorigenesis assay.

Figure 1:

(A) Schematic representation of long-term tumorigenesis assay design. Tumor free survival of Mlh1+/+ and Mlh1+/− mice post (B) 100 or 250 cGy γ-rays, or (C) 10 or 100 cGy 56Fe ions (n=36–44, number of Mlh1+/+ or Mlh1−/− mice used for each radiation exposure). (D) Tumor free survival of Mlh1+/+ mice post 0, 100 or 250 cGy γ-rays, or 10 or 100 cGy 56Fe ions. (E) Tumor free survival of Mlh1+/− mice post 0, 100 or 250 cGy γ-rays, or 10 or 100 cGy 56Fe ions. (F) Days post-irradiation to reach 70% survival. Variance between groups is not significantly different.