Table 2.
Changes in Clinical Parameters before and after Kidney Donation.
| Before kidney donation | After kidney donation | p value | ||||
|---|---|---|---|---|---|---|
| Body weight (kg) | 53.8±9.1 | 51.7±8.9 | <0.01 | |||
| Body mass index (kg/m2) | 22.1±3.2 | 21.2±2.9 | <0.01 | |||
| SBP (mmHg) | 122.5±16.1 | 124.6±14.3 | 0.47 | |||
| DBP (mmHg) | 76.0±9.7 | 78.1±10.8 | 0.28 | |||
| MBP (mmHg) | 91.1±11.5 | 93.4±11.1 | 0.25 | |||
| Heart rate (/min) | 66.6±9.8 | 74.5±11.2 | <0.01 | |||
| sCr (mg/dL) | 0.71±0.11 | 1.09±0.17 | <0.01 | |||
| eGFR (mL/min/1.73 m2) | 74.4±6.4 | 46.8±7.2 | <0.01 | |||
| CKD stages | ||||||
| Stage 1 | 0 | 0 | ||||
| Stage 2 | 10 | 0 | ||||
| Stage 3A | 0 | 6 | ||||
| Stage 3B | 0 | 4 | ||||
| Stage 4 | 0 | 0 | ||||
| Stage 5 | 0 | 0 | ||||
| Plasma AGT (mg/mL) | 15.0±3.5 | 24.3±5.8 | <0.01 | |||
| Plasma AngII (pg/mL) | 10.8±5.7 | 11.0±5.9 | 0.88 | |||
| Log serum hs-CRP (ng/mL) | 2.74±0.51 | 3.81±0.39 | <0.01 | |||
| Log urinary Alb/day (mg/day) | 0.77±0.30 | 0.91±0.24 | 0.20 | |||
| Log urinary AGT/day (mg/day) | 0.86±0.41 | 1.77±0.42 | <0.01 |
SBP: systolic blood pressure, DBP: diastolic blood pressure, MBP: mean blood pressure, sCr: serum creatine, eGFR: estimated glomerular filtration rate, CKD: chronic kidney disease, AGT: angiotensinogen, AngII: angiotensin II, hs-CRP: high-sensitivity C-reactive protein, Alb: albumin