Fig. 4.

miR-4739 is high but BMP-7 is low expressed in patients with pleural fibrosis. Pleural tissue samples were collected from parietal pleura in patients with TPE (TB1, 2, 3) or MPE (Tumor1, 2, 3). Pleura sections were stained with Masson's trichrome staining, in situ hybridization histochemistry and immunofluorescence staining. Blue color showed collagen in the Masson's trichrome stainings (a1-f1). In situ hybridization histochemistry stainings (a2-f2), yellow color showed miR-4739. Red color showed BMP-7 in immunofluorescence stainings (a3-f3). Green color showed calretinin in immunofluorescence staining (a4-f4). (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)