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. 2018 Oct 8;18(2):212–224. doi: 10.1007/s12311-018-0981-y

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — General connectivity increase in cerebellum and brainstem after levodopa in PD patients (N = 24) compared to OFF condition. Result based on eigenvector centrality analysis of resting-state fMRI restricted by a mask involving expanded primary motor, premotor, sensorimotor cortex, basal ganglia, thalamus, brainstem, and cerebellum (blue region). Gray cluster shows the pairwise ON vs. OFF difference (p < 0.05 with family-wise error correction at the cluster level)