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. 2019 Apr 1;10(4):296. doi: 10.1038/s41419-019-1516-2

Fig. 3. Knockdown of LINC01048 promoted CSCC cell apoptosis in vitro and suppressed CSCC cell growth in vivo.

Fig. 3

a, b Apoptotic change of SCC13 and SCL-1 cells transfected with sh-LINC01048#2, sh-LINC01048#3, or sh-NC was observed using flow cytometric analysis and caspase-3 activity test. c The effects of LINC01048 depletion on the levels of apoptosis-related proteins were examined with western blotting. d Tumors derived from SCC13 cells transfected with sh-LINC01048 or sh-NC was observed. e, f The tumor weight and tumor volume in sh-LINC01048 group or in sh-NC group were measured and calculated. g The expression level of LINC01048 in tumors of different groups. **p < 0.01 vs. control group