Fig. 4. NK cells express B220 activation mark after p53 restoration.
Cell suspensions from Rag1-/- mouse lungs bearing orthotopically transplanted KPr lung adenocarcinomas treated with corn oil (Control) or tamoxifen (Restored) were subjected to multiparameter flow cytometry. a Cells gated to include live singlets that are CD45pos. are plotted on NK1.1 x DX5. NK1.1pos.;DX5pos. cells are gated (top) and then plotted for B220pos.;NKp46pos. histogram. b Splenocytes also shown for comparison. c Analysis of significance between control and restored groups was performed by t-test