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. 2019 Mar 26;10:485. doi: 10.3389/fmicb.2019.00485

Table 2.

Mutations in the quinolone resistance determining regions (QRDR) of GyrA (DNA Gyrase), ParC, and ParE (DNA topoisomerase IV) of the quinolone resistant strains.

Strain GyrA ParC ParE



Synonymous substitution Non-synonymous substitution Synonymous substitution Non-synonymous substitution Synonymous substitution Non-synonymous substitution
C3044, C3046 S84F P34P, V74V S80F, D84G V70V, Q73Q, G104G L411L, L430L, L442L, V458V
C3910 S84F, E88K P34P, V74V S80Y, D84Y V70V, Q73Q, G104G L411L, L430L, L442L, V458V
C3922 S84F, E88K P34P, V74V S80Y, D84Y V70V, Q73Q, G104G L411L, L430L, L442L, V458V
C5110 S84F P34P, V74V S80Y V70V, Q73Q, G104G L411L, L430L, L442L, V458V

GyrB is not represented given that no mutations were observed. Synonymous substitutions are marked in bold.