Table 1.

Transgenic expression of tRXRα promotes colorectal carcinogenesis

Model	DSS alone				AOM alone
Group of mice	WT	tRXRα			WT	tRXRα
Number of mice	12	8	1	1	6	4	2
Tumors of mouse	0	0	2	1	0	0	1
Mice with tumours	0		20%		0	33.4%
P value	0.05211				0.0607

AOM azoxymethane, DSS dextran sodium sulfate, tRXRα trunacted retinoid X receptor α, WT wild type