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. 2019 Mar 26;13:34. doi: 10.3389/fnana.2019.00034

Figure 6.

Figure 6

The claustrum shows core and shell expression in the macaque. This figure shows the expression of Crym (A,F), Synpr (B,G), Nr4a2 (C,H), Ntng2 (D,I) and Ctgf (E,J) in the macaque claustrum. Panels (A–E) represent sections taken at the level of anterior temporal cortex. Panels (F–J) represent sections taken caudal to the dorsal endopiriform nucleus (DEn). Crym expression forms a shell at the edges of Synpr, Nr4a2 and Ntng2 in the ventral claustrum (VCl) (asterisk, F). The upper portion of the principal claustrum (ClP) has a more even distribution of Crym, Synpr, Nr4a2 and Ntng2, which is homologous with the dorsal claustrum (DCl) in rodents (upper arrows, A–D). There is a lower portion of the ClP that has weaker Synpr, Nr4a2, and Ntng2 expression, appears outside the “shell” region of the VCl and has weak mixed Crym expression (outlined region, F–I). These criteria, alongside the topological argument, identify this region as a continuation of the DCl traveling around and under the temporal cortex (lower arrows, B–D; outlined region, F–I). Panel (E) shows a selective expression of Ctgf in the DEn. The DEn appears directly caudal to the piriform cortex and disappears in further caudal sections (J). Scale bar - 4,200 μm. Images (A–J) © 2009 Allen Institute for Brain Science. NIH Blueprint Non-Human Primate (NHP) Atlas (2009). Available online at: blueprintnhpatlas.org.