Table 2.
Number of pathogens detected and performance outline of FilmArray ME Panel.
| Organism identified | FA ME panel detection (n) | True positive | False positive | True negative | False negative | Sensitivity | Specificity (%) |
|---|---|---|---|---|---|---|---|
| BACTERIA | |||||||
| E. Coli K1 | 1 | 1 | 0 | 704 | 0 | 100% | 100 |
| H. influenzae | 0 | 0 | 0 | 705 | 0 | N/A | 100 |
| L. monocytogenes | 0 | 0 | 0 | 705 | 0 | N/A | 100 |
| N. meningitidis | 0 | 0 | 0 | 705 | 0 | N/A | 100 |
| S. agalactiae | 2 | 2 | 0 | 703 | 0 | 100% | 100 |
| S. pneumoniae | 4 | 3 | 1 | 701 | 0 | 100% | 99.80 |
| YEAST | |||||||
| C. neoformans/gattii | 1 | 1 | 0 | 704 | 1 | 50% | 100 |
| FA ME panel detection (n) | Concordant positive | Discordant positive | % Concordance | ||||
| VIRUSES | |||||||
| CMV | 2 | 1 | 1 | 50 | |||
| EV | 6 | 6 | 0 | 100 | |||
| HSV-1 | 2 | 2 | 0 | 100 | |||
| HSV-2 | 3 | 3 | 0 | 100 | |||
| HHV-6 | 13 | 3 | 10 | 23.10 | |||
| HPeV | 4 | 4 | 0 | 100 | |||
| VZV | 7 | 7 | 0 | 100 | |||
Sensitivity and specificity calculations for bacteria and yeast are based on comparison to gold standard culture results. Concordance for viruses is based on chart review to determine the clinical significance of cases.