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. 2019 Mar 19;9(4):605–617. doi: 10.1002/2211-5463.12606

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© 2019 The Authors. Published by FEBS Press and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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GRK6 expression is induced by 5‐Aza‐CdR treatment in LADC cell lines. (A) qPCR results showed that the expression of the GRK6 gene in A549 and A427 cells was significantly less than that in 16HBE cells (*P < 0.05, Student's t test). Data are presented as means ± SD. (B) The methylation status of the GRK6 gene promoter was analyzed by BSP in the different cells. (C) GRK6 mRNA expression levels were analyzed by qPCR in the indicated cells treated with 5‐Aza‐CdR (*P < 0.05, Student's t test). Data are presented as means ± SD. The data represent the results from three independent experiments.