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. 2019 Mar 19;9(4):605–617. doi: 10.1002/2211-5463.12606

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© 2019 The Authors. Published by FEBS Press and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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The effects of GRK6 on cell migration and invasion. (A) After transfection with siRNA or pcDNA3.1‐GRK6, the expression of the GRK6 protein decreased or increased significantly, respectively (*P < 0.05, Student's t test). Data are presented as means ± SD. (B) Upregulation of GRK6 significantly inhibited cell migration and invasion (*P < 0.05, Student's t test). Data are presented as means ± SD. (C) Downregulation of GRK6 significantly promoted cell migration and invasion (*P < 0.05, Student's t test). Original magnification: ×200. Data are presented as means ± SD. The data represent the results from three independent experiments.