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. 2019 Mar 26;13:264. doi: 10.3389/fnins.2019.00264

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Copyright © 2019 Wu, Huang, Gong, Xu, Lu, Sheng and Ni.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ICV administration of MitoTEMPO improves depression-like behavior and reduces circulatory corticosterone level in Dex offspring. Male Dex offspring received ICV administration of MitoTEMPO (0.02 or 0.2 μmol/kg, 5 μL/day) for 4 days. Sucrose preference test (A), FST (B) and corticosterone concentration in blood (C) were then determined. Data are presented as means ± SEM (n = 6/group). ^∗∗P < 0.01 vs. control.