Table 2.
Perioperative variables
| Variable | All patients (n = 700) | With complete handover (n = 102) | Without complete handover (n = 598) | P value |
|---|---|---|---|---|
| Benzodiazepines at preoperative night | 79 (11.3) | 12 (11.8) | 67 (11.2) | 0.869 |
| Type of anesthesia | 0.233 | |||
| General | 578 (82.6) | 80 (78.4) | 498 (83.3) | |
| Combined epidural-general | 122 (17.4) | 22 (21.6) | 100 (16.7) | |
| Intraoperative medication | ||||
| Nitrous oxide | 523 (74.7) | 73 (71.6) | 450 (75.3) | 0.429 |
| Sevoflurane | 501 (71.6) | 73 (71.6) | 428 (71.6) | 0.999 |
| Benzodiazepines | 326 (46.6) | 51 (50.0) | 275 (46.0) | 0.453 |
| Propofol | 634 (90.6) | 97 (95.1) | 537 (89.8) | 0.091 |
| Etomidate | 273 (39.0) | 38 (37.3) | 235 (39.3) | 0.696 |
| Glucocorticoids | 646 (92.3) | 98 (96.1) | 548 (91.6) | 0.120 |
| Duration of anesthesia, min | 288 (211, 386) | 416 (274, 586) | 274 (202, 362) | < 0.001 |
| Duration of surgery, min | 200 (126, 292) | 312 (190, 479) | 189 (119, 271) | < 0.001 |
| Type of surgery | 0.153 | |||
| Superficial and transurethral | 69 (9.9) | 4 (3.9) | 65 (10.9) | |
| Intra-abdominal | 475 (67.9) | 71 (69.6) | 404 (67.6) | |
| Intra-thoracic | 120 (17.1) | 21 (20.6) | 99 (16.5) | |
| Spinal and extremital | 36 (5.1) | 6 (5.9) | 30 (5.0) | |
| Grade of surgerya | 0.006 | |||
| Intermediate | 42 (6.0) | 0 (0.0) | 42 (7.0) | |
| Major or complex | 658 (94.0) | 102 (100.0) | 556 (93.0) | |
| Cardiac risk of surgeryb | 0.281 | |||
| Low | 33 (4.7) | 2 (2.0) | 31 (5.2) | |
| Intermediate | 658 (94.0) | 98 (96.1) | 560 (93.6) | |
| High | 9 (1.3) | 2 (2.0) | 7 (1.2) | |
| Estimated blood loss, ml | 150 (50, 450) | 400 (100, 800) | 100 (40, 400) | < 0.001 |
| Total intraoperative fluid, ml | 2510 (1600, 3700) | 3600 (2488, 5313) | 2350 (1600, 3413) | < 0.001 |
| Intraoperative blood transfusion | 114 (16.3) | 30 (29.4) | 84 (14.0) | < 0.001 |
| ICU admission with intubation | 382 (54.6) | 82 (80.4) | 300 (50.2) | < 0.001 |
| Prophylactic dexmedetomidine | 350 (50.0) | 52 (51.0) | 298 (49.8) | 0.830 |
| Postoperative analgesia | 0.051 | |||
| None | 73 (10.4) | 5 (4.9) | 68 (11.4) | |
| PCIA | 516 (73.7) | 75 (73.5) | 441 (73.7) | |
| PCEA | 111 (15.9) | 22 (21.6) | 89 (14.9) | |
| Other sedatives/analgesics within 7 days | ||||
| Propofol | 357 (51.0) | 80 (78.4) | 277 (46.3) | < 0.001 |
| Benzodiazepines | 58 (8.3) | 11 (10.8) | 47 (7.9) | 0.322 |
| Opioids | 201 (28.7) | 32 (31.4) | 169 (28.3) | 0.521 |
| NSAIDs | 229 (32.7) | 31 (30.4) | 198 (33.1) | 0.589 |
| Pathologically diagnosed cancer | 561 (80.1) | 84 (82.4) | 477 (79.8) | 0.545 |
Data are presented as number (%), or median (interquartile range)
ICU intensive care unit, PCIA patient-controlled intravenous analgesia, PCEA patient-controlled epidural analgesia, NSAIDs non-steroid anti-inflammatory drugs
aRated according to NICE Guidance of Routine preoperative tests for elective surgery [18]
bRated according to ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery [19]