Table 4.

Factors in association with postoperative delirium

Variable	Univariate analysesa		Multivariate analysisb
	OR (95% CI)	P value	OR (95% CI)	P value
Complete handover of anesthesia care	1.687 (1.006–2.828)	0.041	1.787 (1.012–3.155)	0.046
Age, years	1.049 (1.019–1.081)	0.001	1.041 (1.008–1.074)	0.013
Body mass index, kg/m2	0.902 (0.853–0.954)	< 0.001	0.930 (0.878–0.985)	0.013
Previous stroke	1.692 (1.083–2.644)	0.021	1.785 (1.104–2.886)	0.018
Preoperative albumin < 30 g/L	2.473 (1.301–4.702)	0.006	1.700 (0.838–3.450)	0.142
Intraoperative use of etomidate	1.823 (1.212–2.742)	0.004	1.373 (0.879–2.143)	0.163
ICU admission with intubation	2.109 (1.365–3.257)	0.001	1.859 (1.162–2.974)	0.010
Prophylactic dexmedetomidinec	0.345 (0.222–0.537)	< 0.001	0.354 (0.223–0.560)	< 0.001
Postoperative propofol within 7 daysd	1.570 (1.038–2.373)	0.032	–	–
Pathologically diagnosed cancer	0.519 (0.328–0.820)	0.005	0.610 (0.369–1.007)	0.053

^aPostoperative delirium within 7 days was modeled as a function of a single factor in the univariate logistic regression analyses

^bPostoperative delirium within 7 days was modeled as a function of all factors with a P value < 0.05 in the univariate analyses. Multivariate Logistic regression analysis was performed using a Enter procedure. Hosmer–Lemeshow test of goodness of fit of the model: χ² = 7.651, df = 8, P = 0.468

^cAdministered as a continuous infusion at a rate of 0.1 µg/kg/h from ICU admission to 8 am of next morning [15]

^dNot included in multivariable analysis because of correlation with ICU admission with intubation