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. 2019 Apr 1;9:5404. doi: 10.1038/s41598-019-41820-y

Table 3.

Stepwise multiple regression analysis of explanatory variables for the dose-adjusted C0 of lenvatinibTable 3. Stepwise multiple regression analysis of explanatory variables for the dose-adjusted C0 of lenvatinib.

Explanatory variable Slope SE SRC P- value R 2
0.226
CYP3A4 genotype (*1G allele = 1) −2.05 0.75 −0.397 0.010
Total bilirubin (mg/dL) 3.67 1.77 0.300 0.046
Intercept =  6.39 1.66

C0, predose concentration.

SE, standard error; SRC, standardized regression coefficient.