Table 1. Summary of the main functional regions of proteins encoded by key genes.
Gene name | Protein name | Uniport entry | Organism | Length | Main functional regions | |
---|---|---|---|---|---|---|
Regions | Description | |||||
FN1 | Fibronectin | P02751 | Homo sapiens | 2386 | 52–272 | Fibrin- and heparin-binding 1 |
308–608 | Collagen-binding | |||||
464–477 | Critical for collagen binding | |||||
1267–1540 | Cell-attachment | |||||
1721–1991 | Heparin-binding 2 | |||||
1813–1991 | Binds to FBLN1 | |||||
1992–2102 | Connecting strand 3 (CS-3) (V region) | |||||
2206–2337 | Fibrin-binding 2 | |||||
SDC4 | Syndecan-4 | P31431 | Homo sapiens | 198 | - | - |
NMU | Neuromedin-U | P48645 | Homo sapiens | 174 | - | - |
LPAR5 | Lysophosphatidic acid receptor 5 | Q9H1C0 | Homo sapiens | 372 | - | - |
BCL2 | Apoptosis regulator Bcl-2 | P10415 | Homo sapiens | 239 | - | - |
CXCL12 | Stromal cell-derived factor 1 | P48061 | Homo sapiens | 93 | 29–33 | Receptor and heparin binding |
39–41 | Receptor binding | |||||
41–51 | Heparin binding | |||||
48–50 | Receptor binding | |||||
60–70 | Receptor binding |