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. 2019 Apr 2;39(4):BSR20182018. doi: 10.1042/BSR20182018

Figure 3. FBXL19-AS1 acted as a sponge of miR-718.

Figure 3

(A) The predicted miR-718 binding sites in FBXL19-AS1. (B) Dual luciferase reporter assay showed that miR-718 mimics significantly decreased the luciferase activity of FBXL19-AS1-Wt in BC cells. (C) FBXL19-AS1 inhibition increased miR-718 expression in BC cells. (D) RIP assay showed that miR-718 and FBXL19-AS1 were both enriched in Ago2-containing miRNAs. (E,F) QRT-PCR was used to explore miR-718 expression in BC tissues and cell lines. (G) FBXL19-AS1 expression was negatively correlated with miR-718 expression in BC tissues. *P<0.05.