Kaplan-Meier curves show cumulative brain metastases in patients with non-small cell lung cancer. Patients were grouped according to P-AKT expression levels. A. Negative, low, medium and high expression of 4 groups; B. Negative, positive expression (including low, medium, high) 2 groups; C. Points (negative + low) and (middle + high) expression of 2 groups; D. scores (negative + low + medium) and high expression of 2 groups; the results showed that patients with high P-AKT expression had an increased brain metastasis rate.