Table III.
Results of selected laboratory tests at the time of diagnosis and at 48 h from the onset of AP
| Variable | Time point | AP (n = 83) | Control (n = 30) | P-value¥ |
|---|---|---|---|---|
| Amylase [U/l] | Diagnosis 48 h |
592 (292–1200) 80 (61–123)* |
28.5 (24.0–42.0) | < 0.001 |
| Lipase [U/l] | Diagnosis 48 h |
1200 (623–1994) 67 (36–173)* |
24.8 (22.0–32.0) | < 0.001 |
| C-reactive protein [mg/l] | Diagnosis 48 h |
2.02 (0.70–5.46) 2.18 (0.61–7.93)* |
0.26 (0.24–0.34) | NS |
| Sedimentation rate [mm/h] | Diagnosis 48 h |
14.5 (6.0–24.3) 20.0 (12.0–30.0) |
12.0 (10.0–14.0) | 0.012 |
| Leukocytes [× 103/mm3] | Diagnosis 48 h |
9.3 (7.1–11.4) 7.98 (6.26–10.0)* |
7.9 (6.9–8.7) | 0.001 |
| Neutrophils [× 103/mm3] | Fiagnosis 48 h |
7.13 ±3.73 5.41 ±2.77* |
4.74 ±0.94 | 0.005 |
| Lymphocytes [× 103/mm3] | Diagnosis 48 h |
1.78 ±0.88 2.13 ±1.39* |
2.65 ±0.83 | < 0.001 |
| Monocytes [× 103/mm3] | Diagnosis 48 h |
0.65 ±0.24 0.74 ±1.08 |
0.42 ±0.16 | < 0.001 |
| RDW (%) | Diagnosis 48 h |
15.5 (14.8–16.4) 15.4 (14.6–16.5) |
15.6 (15.5–16.0) | NS |
| MPV [fl] | Diagnosis 48 h |
7.82 (7.0–8.9) 7.76 (7.0–9.2) |
10.1 (8.9–10.9) | NS |
| PDW (%) | Diagnosis 48 h |
18.0 (17.2–19.0) 18.1 (17.4–19.0) |
16.8 (16.6–17.2) | NS |
| Platelet count [× 103 μl] | Diagnosis 48 h |
228.6 ±71.98 233.2 ±79.36 |
269.2 ±38.39 | 0.001 |
| Haematocrit (%) | Diagnosis 48 h |
37.9 ±5.24 37.7 ±4.88 |
40.5 ±1.66 | < 0.001 |
| Platelets [× 103/mm3] | Diagnosis 48 h |
0.18 ±0.06 2.29 ±18.64 |
0.24 ±0.04 | < 0.001 |
| Glucose [g/dl] | Diagnosis 48 h |
99.0 (88.0–122.0) 91.0 (82.0–106.5)* |
93.0 (86.0–98.0) | < 0.001 |
| Albumin [g/l] | Diagnosis 48 h |
3.9 (3.6–4.0) 3.9 (3.3–4.0) |
4.2 (4.0–4.3) | < 0.001 |
| Urea [mg/dl] | Diagnosis 48 h |
26.7 ±11.98 24.4 ±12.69* |
28.1 ±6.92 | NS |
| Creatinine [mg/dl] | Diagnosis 48 h |
0.84 ±0.47 0.88 ±0.77 |
0.94 ±0.11 | NS |
| Calcium [mg/dl] | Diagnosis 48 h |
9.0 (8.7–9.2) 9.0 (9.0–9.2) |
10.1 (9.7–10.2) | < 0.001 |
| IL-35 [ng/ml] | Diagnosis 48 h |
5.91 (4.21–7.90) 6.79 (4.42–9.62)* |
25.53 (12.79–54.73) | < 0.001 |
| Pentraxin-3 [ng/ml] | Diagnosis 48 h |
6.75 (4.42–9.62) 6.75 (4.74–9.06) |
7.64 (6.58–8.62) | NS |
*
There is a significant difference between 24-h and 48-h levels (p < 0.001, p < 0.001, p = 0.008, p = 0.001, p < 0.001, p = 0.022, p = 0.006, p = 0.001, and p = 0.015, respectively).
¥
t-tests were used for analysis. RDW – red blood cell distribution width, MPW – mean platelet volume, PDW – platelet distribution width, IL-35 – interleukin-35.