Table 6.
The distribution of methylated genes of AEG on DNA methylation in APP/PS1 and SAMP8 mice.
| Sample | Group | Total_bases | Tag_count | Tags/Kb |
|---|---|---|---|---|
| SAMP8 | CDS_Exons | 92,770,739 | 10,520,478 | 113 |
| 5’UTR_Exons | 6,817,714 | 675,919 | 99 | |
| 3’UTR_Exons | 30,830,041 | 3,147,020 | 102 | |
| Introns | 1,469,823,225 | 154,457,401 | 105 | |
| TSS_up_1kb | 29,802,851 | 1,894,436 | 64 | |
| TSS_up_5kb | 133,470,634 | 8,597,890 | 64 | |
| TSS_up_10kb | 239,135,684 | 15,695,506 | 66 | |
| TES_down_1kb | 31,715,036 | 1,963,976 | 62 | |
| TES_down_5kb | 137,780,250 | 8,829,933 | 64 | |
| TES_down_10kb | 242,815,081 | 16,089,066 | 66 | |
| AEG-SAMP8 | CDS_Exons | 92,770,739 | 10,262,220 | 110.62 |
| 5’UTR_Exons | 6,817,714 | 662,568 | 97.18 | |
| 3’UTR_Exons | 30,830,041 | 3,082,650 | 99.99 | |
| Introns | 1,469,823,225 | 150,628,394 | 102.48 | |
| TSS_up_1kb | 29,802,851 | 1,858,553 | 62.36 | |
| TSS_up_5kb | 133,470,634 | 8,429,922 | 63.16 | |
| TSS_up_10kb | 239,135,684 | 15,383,988 | 64.33 | |
| TES_down_1kb | 31,715,036 | 1,929,853 | 60.85 | |
| TES_down_5kb | 137,780,250 | 8,680,528 | 63 | |
| TES_down_10kb | 242,815,081 | 15,790,406 | 65.03 | |
| AEG-APP/PS1 | CDS_Exons | 92,770,739 | 9,966,285 | 107.43 |
| 5’UTR_Exons | 6,817,714 | 650,467 | 95.41 | |
| 3’UTR_Exons | 30,830,041 | 3,040,614 | 98.63 | |
| Introns | 1,469,823,225 | 149,238,024 | 101.53 | |
| TSS_up_1kb | 29,802,851 | 1,829,107 | 61.37 | |
| TSS_up_5kb | 133,470,634 | 8,285,235 | 62.08 | |
| TSS_up_10kb | 239,135,684 | 15,097,669 | 63.13 | |
| TES_down_1kb | 31,715,036 | 1,896,834 | 59.81 | |
| TES_down_5kb | 137,780,250 | 8,520,685 | 61.84 | |
| TES_down_10kb | 242,815,081 | 15,519,964 | 63.92 | |
| APP/PS1 | CDS_Exons | 92,770,739 | 11,036,360 | 118.96 |
| 5’UTR_Exons | 6,817,714 | 687,146 | 100.79 | |
| 3’UTR_Exons | 30,830,041 | 3,215,666 | 104.3 | |
| Introns | 1,469,823,225 | 158,021,162 | 107.51 | |
| TSS_up_1kb | 29,802,851 | 1,926,517 | 64.64 | |
| TSS_up_5kb | 133,470,634 | 8,726,063 | 65.38 | |
| TSS_up_10kb | 239,135,684 | 15,913,380 | 66.55 | |
| TES_down_1kb | 31,715,036 | 2,005,028 | 63.22 | |
| TES_down_5kb | 137,780,250 | 8,981,573 | 65.19 | |
| TES_down_10kb | 242,815,081 | 16,369,504 | 67.42 | |
| Control | CDS_Exons | 92,770,739 | 9,678,453 | 104.33 |
| 5’UTR_Exons | 6,817,714 | 640,382 | 93.93 | |
| 3’UTR_Exons | 30,830,041 | 2,988,843 | 96.95 | |
| Introns | 1,469,823,225 | 146,269,536 | 99.52 | |
| TSS_up_1kb | 29,802,851 | 1,798,551 | 60.35 | |
| TSS_up_5kb | 133,470,634 | 8,120,448 | 60.84 | |
| TSS_up_10kb | 239,135,684 | 14,814,071 | 61.95 | |
| TES_down_1kb | 31,715,036 | 1,863,605 | 58.76 | |
| TES_down_5kb | 137,780,250 | 8,358,614 | 60.67 | |
| TES_down_10kb | 242,815,081 | 15,226,423 | 62.71 |
Alcohol (AEG) extracts from G. lucidum by gavage.