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. 2019 Feb;39(1):9–17. doi: 10.14639/0392-100X-1905

Table I.

Comparison of clinical features of HPV-investigated and not investigated OPSCC patient groups.

Group Sex Age (years) Stagea Surgery Smokea Alcohola Recurrencea DSDa FUa (months)
M/F Mean ± SD 0-1 2 3 4 T/N Y/Nb Y/Nc Y/N DFS (months) Y/N
1992-2010 142/33 59.5 ± 9.6 9 25 37 69 49/45 24/27 32/10 63/18 57.8 ± 50.4 49/91 69.7 ± 54.1
Tested 45/8 59.9 ± 10.2 4 13 15 21 20/20 14/15 12/7 22/3 60.1 ± 52.7 24/24 74.8 ± 58.1
Untested 97/25 58.1 ± 10.72 5 12 22 48 29/25 10/12 20/3 41/15 54.2 ± 45.2 25/67 60 ± 44.3
p Ns Ns Ns Ns Ns Ns Ns Ns Ns Ns
2011-2015 65/16 63.5 ± 10.4 6 6 19 48 32/33 48/22 36/25 15/44 23.9 ± 14.4 17/60 22.0 ± 14.4
Tested 56/15 63.8 ± 10.3 5 6 16 43 25/25 42/21 29/25 11/42 25.2 ± 14.6 17/53 22.1 ± 14.7
Untested 9/1 61.5 ± 11.7 1 0 3 5 7/8 6/1 7/0 4/2 12.5 ± 4.5 0/7 20.7 ± 12.6
p Ns Ns Ns Ns Ns 0.033 0.031 0.000 Ns Ns

a: data not available for the complete case series

b: never smoker or former smoker (any number) quitting more than 5 years before cancer diagnosis

c: clinical or laboratory evidence of alcoholism

M: male; F: female; SD: standard deviation; Y: yes; N: no; DFS: disease-free survival; DSD: disease-specific death; FU: follow-up; Ns: not significant.