Table II.

Scores for typical ibuprofen-responsive symptoms at baseline and after intake of the first dose of the combination 200 mg ibuprofen plus 30 mg pseudoefedrine (irrespective of taking 1 or 2 tablets) as well as intra-individual change after firts intake.

Score	Baseline	After first intake	Reduction	% Reduction
TIRS	4.62 ± 2.19	1.87 ± 1.69	2.75 ± 1.89	60.0 ± 33.2
TPRS	4.89± 2.33	2.50 ± 1.74	2.39 ± 1.93	46.3 ± 64.6
NSS	3.33 ± 2.03	1.81 ±1.58	1.52 ± 1.53	45.4 ± 41.0
TSS	4.22 ± 1.65	2.02 ± 1.42	2.20 ± 1.41	52.8 ± 29.7

TIRS, typical ibuprofen-responsive symptoms consisting of headache, pharyngeal pain, joint pain and fever; TPRS, typical pseudoephedrine-responsive symptoms consisting of congested nose, congested sinus and runny nose; NSS, non-specific-symptoms consisting of sneezing, fatigue, dry cough, cough with expectoration; TSS < total symptoms consisting of all 11 symptoms. Data are means ± SD on a scale of 0 (smallest extent) to 10 (greatest extent) or % change (reproduced from Klimek et al., 2017 ⁸).