Trajectories of MMSE and RBANS delayed memory index score over 2 years grouped by 18F-FDG (A, B) and 18F-AV45 (C, D) positivity based on visual reading at baseline. The Δslope (non-standardized β) indicates the difference in change in cognitive score per year between PET+ and PET- subjects, adjusted for covariates. Abbreviations: CI confidence interval, MMSE Mini-Mental state examination, PET positron emission tomography, SE standard error.