Fig. 3.

Receiver operating characteristic curves of the strongest (i.e., highest AUC) one-, two- and three- variable models describing MCI-to-AD dementia conversion over 1 year (N = 42). Panel A (left column) shows the strongest single imaging biomarker variables, whereas panel B (left column) shows the strongest single cognitive variables. The middle and right columns show the two- and three-variable models for which the discriminating ability significantly improved after addition of an extra biomarker. Abbreviations: AUC area under the curve, CGM cortical grey matter volume, Delayed RBANS delayed memory index score, FDG 18F-fluorodeoxyglucose PET in the precuneus, HV hippocampal volume, MMSE Mini-Mental state examination, Visuo RBANS visuospatial construction index score.