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. 2018 Dec 27;7(3):655–678. doi: 10.1016/j.jcmgh.2018.12.007

Table 4.

Summary of Histopathologic Findings at P18–P25

P18–P25 ID Weight, g Sex Applied Teitelbaum et al7 grade Surface epithelial injury Crypt dilation Intraepithelial apoptotic remnants Goblet cell hyperplasia Mucins in crypts
Bacteria in crypts Enterocyte adherence Leukocytes
Mucin shift to PAS Basal Surface Mucus retention Granulocytes Lymphocytes
WT 29.12.8-9 ND ND 0 - - - No No AB PAS - - No - -
WT 23.3-9-5 11.1 F 0 - - - No No AB PAS - - No - -
WT 22.9.10CA-2 10.1 F 0 - - - No No AB PAS - - No - -
WT 5.1.9-9 12.23 M 0 - - - No No AB PAS - - No - -
WT/hypo 29.12.8-5 ND ND 0 - - - No No AB PAS - - No - +
WT/hypo 23.3-9-6 12.1 F 0 - - - No No AB PAS - - No - -
WT/hypo 22.9.10CA-7 84 F 0 - - - No No AB PAS - - No - -
WT/hypo 22.9.10 CA-8 8.9 F 0 - - - No No AB PAS - - No - -
Hypo/hypo 29.12.8-8 ND ND III/IV Marked ++ ++ Degenerated Yes PAS AB + + Yes ++ -
Hypo/hypo 23.3-9-4 9.4 M II Moderate ++ + Yes Yes PAS/ foamy AB PAS/ foamy AB ++ - No - +
Hypo/hypo 22.9.10CA-3 8.5 M III/IV Marked +/++ ++ Yes + degenerated Degenerated degenerated Atypical AB + - No ++ +
Hypo/hypo 22.9.10 CA-10 7.8 F II Moderate ++/+++ ++ Yes Yes PAS/ foamy AB PAS/ foamy AB ++ - No + +
Hypo/hypo 5.1.9-7 8.8 M IV/V Marked ++/+++ +++ Yes + degenerated Yes PAS/ foamy AB PAS/ foamy AB +/++ ++ Yes + +
Minimal Mild + Mild + Mild + Mild + Normal - (<4/HPF)
0–V Mild Moderate ++ Moderate ++ Yes/no Yes/no Moderate ++ Moderate ++ Yes/no Mild + (5–15/HPF)
Moderate Marked +++ Marked +++ Marked +++ Moderate ++ (20–30/HPF)
Marked

NOTE. See the Materials and Methods section for details regarding histopathologic grading.

ND, not determined.