Table 4.
P18–P25 | ID | Weight, g | Sex | Applied Teitelbaum et al7 grade | Surface epithelial injury | Crypt dilation | Intraepithelial apoptotic remnants | Goblet cell hyperplasia | Mucins in crypts |
Bacteria in crypts | Enterocyte adherence | Leukocytes |
||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mucin shift to PAS | Basal | Surface | Mucus retention | Granulocytes | Lymphocytes | |||||||||||
WT | 29.12.8-9 | ND | ND | 0 | - | - | - | No | No | AB | PAS | - | - | No | - | - |
WT | 23.3-9-5 | 11.1 | F | 0 | - | - | - | No | No | AB | PAS | - | - | No | - | - |
WT | 22.9.10CA-2 | 10.1 | F | 0 | - | - | - | No | No | AB | PAS | - | - | No | - | - |
WT | 5.1.9-9 | 12.23 | M | 0 | - | - | - | No | No | AB | PAS | - | - | No | - | - |
WT/hypo | 29.12.8-5 | ND | ND | 0 | - | - | - | No | No | AB | PAS | - | - | No | - | + |
WT/hypo | 23.3-9-6 | 12.1 | F | 0 | - | - | - | No | No | AB | PAS | - | - | No | - | - |
WT/hypo | 22.9.10CA-7 | 84 | F | 0 | - | - | - | No | No | AB | PAS | - | - | No | - | - |
WT/hypo | 22.9.10 CA-8 | 8.9 | F | 0 | - | - | - | No | No | AB | PAS | - | - | No | - | - |
Hypo/hypo | 29.12.8-8 | ND | ND | III/IV | Marked | ++ | ++ | Degenerated | Yes | PAS | AB | + | + | Yes | ++ | - |
Hypo/hypo | 23.3-9-4 | 9.4 | M | II | Moderate | ++ | + | Yes | Yes | PAS/ foamy AB | PAS/ foamy AB | ++ | - | No | - | + |
Hypo/hypo | 22.9.10CA-3 | 8.5 | M | III/IV | Marked | +/++ | ++ | Yes + degenerated | Degenerated | degenerated | Atypical AB | + | - | No | ++ | + |
Hypo/hypo | 22.9.10 CA-10 | 7.8 | F | II | Moderate | ++/+++ | ++ | Yes | Yes | PAS/ foamy AB | PAS/ foamy AB | ++ | - | No | + | + |
Hypo/hypo | 5.1.9-7 | 8.8 | M | IV/V | Marked | ++/+++ | +++ | Yes + degenerated | Yes | PAS/ foamy AB | PAS/ foamy AB | +/++ | ++ | Yes | + | + |
Minimal | Mild + | Mild + | Mild + | Mild + | Normal - (<4/HPF) | |||||||||||
0–V | Mild | Moderate ++ | Moderate ++ | Yes/no | Yes/no | Moderate ++ | Moderate ++ | Yes/no | Mild + (5–15/HPF) | |||||||
Moderate | Marked +++ | Marked +++ | Marked +++ | Moderate ++ (20–30/HPF) | ||||||||||||
Marked |
NOTE. See the Materials and Methods section for details regarding histopathologic grading.
ND, not determined.