Skip to main content
. Author manuscript; available in PMC: 2020 Mar 28.
Published in final edited form as: Vaccine. 2019 Mar 4;37(14):2026–2033. doi: 10.1016/j.vaccine.2019.01.002

Table 2.

Public Health Results in a 50-year-old single-year cohort over their remaining lifetimes

Assuming PPSV23 is NOT effective vs. non-bacteremic pneumonia IPD cases IPD deaths NBP cases NBP deaths
Black Population (cohort size = 549,197)
No vaccination 7,617 904 67,258 1,097
High-risk, immunocompromised get PPSV23 7,523 894 67,198 1,097
Present recs, (high-risk get PPSV23, immunocompromised get PCV13/PPSV23) 7,512 893 67,169 1,095
High-risk, immunocompromised get PCV13/PPSV23 7,512 893 66,985 1,092
All get PPSV23 7,484 890 67,199 1,097
All get PCV13/PPSV23 7,469 889 66,755 1,089
General Population (cohort size = 4,034,327)
No vaccination 32,635 3,792 420,634 8,593
High-risk, immunocompromised get PPSV23 32,163 3,745 420,401 8,600
Present recs, (high-risk get PPSV23, immunocompromised get PCV13/PPSV23) 32,110 3,739 420,260 8,590
High-risk, immunocompromised get PCV13/PPSV23 32,104 3,739 419,306 8,558
All get PPSV23 31,975 3,726 420,406 8,600
All get PCV13/PPSV23 31,897 3,718 417,829 8,540
Assuming PPSV23 IS effective vs. non-bacteremic pneumonia IPD cases IPD deaths NBP cases NBP deaths
Black Population (cohort size = 549,197)
No vaccination 7,618 904 67,109 1,087
High-risk, immunocompromised get PPSV23 7,524 894 66,664 1,078
Present recs, (high-risk get PPSV23, 7,512 893 66,636 1,076
immunocompromised get PCV13/PPSV23)
High-risk, immunocompromised get PCV13/PPSV23 7,512 893 66,589 1,075
All get PPSV23 7,485 890 66,333 1,073
All get PCV13/PPSV23 7,469 889 66,149 1,070
General Population (cohort size = 4,034,327)
No vaccination 32,636 3,792 419,602 8,506
High-risk, immunocompromised get PPSV23 32,165 3,745 417,512 8,443
Present recs, (high-risk get PPSV23, 32,112 3,740 417,371 8,433
immunocompromised get PCV13/PPSV23) High-risk, immunocompromised get PCV13/PPSV23 32,105 3,739 41 7,095 8,425
All get PPSV23 31,977 3,726 415,534 8,418
All get PCV13/PPSV23 31,898 3,718 414,360 8,390