Table III.
Univariate cox regression results of each gene in TCGA and GSE21501 cohorts.
| A, TCGA | ||||
|---|---|---|---|---|
| Genes | P-value | Hazard ratio | 95% confidence interval | |
| PSEN1 | 0.00291b | 2.0355 | 1.275 | 3.25 |
| APH1A | 0.025a | 1.598 | 1.061 | 2.408 |
| PSENEN | 0.26 | 1.275 | 0.8353 | 1.946 |
| NCSTN | 0.0469a | 1.7011 | 1.007 | 2.873 |
| PSEN2 | 0.0782 | 1.4574 | 0.9583 | 2.216 |
| APH1B | <0.0001c | 3.2734 | 1.691 | 6.335 |
| B, GSE21501 | ||||
| Genes | P-value | Hazard ratio | 95% confidence interval | |
| PSEN1 | 0.0835 | 1.5772 | 0.9414 | 2.642 |
| APH1A | <0.0001c | 2.724 | 1.517 | 4.892 |
| PSENEN | 0.0248a | 1.7894 | 1.076 | 2.975 |
| NCSTN | 0.371 | 1.257 | 0.7623 | 2.071 |
| PSEN2 | 0.195 | 1.747 | 0.7517 | 4.06 |
| APH1B | 0.153 | 1.4939 | 0.861 | 2.592 |
a
P<0.05
b
P<0.01
c
P<0.0001. PSEN, presenilin; APH1, anterior pharynx-defective 1; PSENEN, presenilin enhancer protein 2; NCSTN, nicastrin; TCGA, The Cancer Genome Atlas.