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Changes in expression level of LDHB after acquisition of cetuximab resistance. Changes in LDHB expression levels in cytoplasmic proteins derived from cetuximab-sensitive cell lines (SW48 and C99) and cell lines that acquired cetuximab resistance (SW48R and C99R). Peak area ratios between the LDHB-specific sequence (SADTLWDIQK) and the internal standard in four CRC cell lines. Data are presented as the mean ± standard deviation of triplicate experiments (Mann-Whitney U test, *P<0.05).
