Table 2.
Comparison of genotype and allele frequencies between cases and controlsa
| Genotype frequency |
Allele frequency |
OR | 95% CI | p value | ||||
|---|---|---|---|---|---|---|---|---|
| 11 | 12 | 22 | 1 | 2 | ||||
| Rs7498665 | ||||||||
| Cases (%) Controls (%) |
359 (34.4) 129 (40.7) | 505 (48.3) 143 (45.1) | 181 (17.3) 45 (14.2) | 1,223 (59) 401 (63) | 867 (41) 233 (37) | 1.26 | 1.04–1.52 | 0.016 |
| Rs7201929 | ||||||||
| Cases (%) Controls (%) |
659 (63.1) 181 (57.1) | 333 (31.9) 111 (35.0) | 53 (5.1) 25 (7.9) | 1,651 (79) 473 (75) | 439 (21) 161 (25) | 0.76 | 0.61–0.94 | 0.011 |
a
Genotype and allele frequencies are shown as absolute numbers (% in parentheses). OR, 95% CI and nominal p value are as calculated by logistic regression with age and sex as covariates (using SPSS 15.0).