Table 4.
Protein | Fold change (+/−) | p-value | Peptides | Product Description | Subcellular Localization (localization [confidence code])* | Product Name Confidence |
---|---|---|---|---|---|---|
PA3661 | 63.0 | < 0.0001 | 2 | Hypothetical protein | Unknown [Class 3] | Class 4 |
PA2505 | 25.1 | < 0.0001 | 10 | Tyrosine porin OpdT | Outer Membrane [Class 2]; Outer Membrane [Class 3]; Outer Membrane Vesicle [Class 1] | Class 1 |
PA4714 | 16.2 | 0.002 | 5 | Conserved hypothetical protein | Unknown (This protein may have multiple localization sites) [Class 3]; Unknown (This protein may have multiple localization sites) [Class 3] | Class 4 |
PA2064 | 10.8 | < 0.0001 | 6 | Copper resistance protein B precursor | Outer Membrane [Class 3]; Outer Membrane Vesicle [Class 1] | Class 2 |
PA2405 | 10.3 | 0.003 | 1 | FpvJ | Unknown [Class 3] | Class 1 |
PA3412 | 10.2 | 0.005 | 3 | Hypothetical protein | Unknown [Class 3] | Class 4 |
PA2807 | 10.1 | 0.004 | 4 | Hypothetical protein | Unknown [Class 3] | Class 4 |
PA4224 | 6.6 | 0.002 | 6 | Pyochelin biosynthetic protein PchG | Cytoplasmic [Class 3] | Class 1 |
PA3445 | 6.2 | 0.002 | 3 | Conserved hypothetical protein | Unknown (This protein may have multiple localization sites) [Class 3]; Unknown (This protein may have multiple localization sites) [Class 3] | Class 4 |
PA4884 | 4.9 | 0.004 | 4 | Hypothetical protein | Periplasmic [Class 3] | Class 4 |
PA2065 | 4.4 | < 0.0001 | 8 | Copper resistance protein A precursor | Periplasmic [Class 2]; Periplasmic [Class 3]; Outer Membrane Vesicle [Class 1] | Class 2 |
PA3920 | 4.0 | 0.003 | 2 | Probable metal transporting P-type ATPase | Cytoplasmic Membrane [Class 3] | Class 3 |
PA3182 | 3.0 | 0.008 | 2 | 6-phosphogluconolactonase | Unknown [Class 3] | Class 1 |
PA0283 | 2.8 | 0.009 | 10 | Sulfate-binding protein precursor | Periplasmic [Class 2]; Periplasmic [Class 3] | Class 2 |
PA3450 | 2.8 | 0.001 | 6 | Probable antioxidant protein | Cytoplasmic [Class 3] | Class 3 |
PA0346 | 2.5 | 0.004 | 6 | Hypothetical protein | Unknown [Class 3] | Class 4 |
PA4923 | 2.3 | 0.010 | 2 | Conserved hypothetical protein | Unknown [Class 3] | Class 4 |
PA3165 | 2.0 | 0.007 | 5 | Histidinol-phosphate aminotransferase | Cytoplasmic [Class 3] | Class 2 |
PA5215 | 1.9 | 0.006 | 1 | Glycine-cleavage system protein T1 | Cytoplasmic [Class 3] | Class 2 |
PA5335 | 1.7 | 0.005 | 1 | Conserved hypothetical protein | Cytoplasmic [Class 3] | Class 4 |
PA4240 | 1.7 | 0.009 | 3 | 30S ribosomal protein S11 | Cytoplasmic [Class 3]; Outer Membrane Vesicle [Class 1] | Class 2 |
PA0473 | 1.7 | 0.006 | 2 | Probable glutathione S-transferase | Cytoplasmic [Class 3] | Class 3 |
PA5188 | 1.7 | 0.010 | 2 | Probable 3-hydroxyacyl-CoA dehydrogenase | Cytoplasmic [Class 3] | Class 3 |
PA3029 | 1.6 | 0.007 | 5 | Molybdopterin biosynthetic protein B2 | Cytoplasmic [Class 3] | Class 2 |
PA4110 | 1.6 | 0.010 | 5 | Beta-lactamase precursor (AmpC) | Periplasmic [Class 1]; Periplasmic [Class 3] | Class 1 |
PA1024 | 1.6 | < 0.0001 | 1 | 2-Nitropropane Dioxygenase | Cytoplasmic [Class 3] | Class 1 |
PA3896 | 1.6 | 0.001 | 2 | Probable 2-hydroxyacid dehydrogenase | Cytoplasmic [Class 2]; Cytoplasmic [Class 3] | Class 3 |
PA4947 | 1.5 | 0.007 | 1 | N-acetylmuramoyl-L-alanine amidase | Unknown [Class 3] | Class 2 |
PA1151 | 1.5 | 0.005 | 3 | Pyocin S2 immunity protein | Cytoplasmic [Class 3] | Class 1 |
PA3243 | 1.5 | 0.001 | 3 | Cell division inhibitor MinC | Cytoplasmic [Class 3] | Class 2 |
PA2572 | −1.6 | 0.008 | 1 | Probable two-component response regulator | Cytoplasmic [Class 3] | Class 3 |
PA0833 | −1.6 | 0.008 | 2 | Hypothetical protein | Outer Membrane [Class 3]; Outer Membrane Vesicle [Class 1] | Class 4 |
PA2476 | −1.7 | 0.008 | 3 | Thiol:disulfide interchange protein DsbG | Periplasmic [Class 3] | Class 2 |
PA5209 | −1.9 | 0.001 | 2 | Hypothetical protein | Unknown (This protein may have multiple localization sites) [Class 3]; Unknown (This protein may have multiple localization sites) [Class 3] | Class 4 |
PA5562 | −1.9 | 0.002 | 5 | Chromosome partitioning protein Spo0J | Cytoplasmic [Class 3] | Class 2 |
PA0265 | −2.0 | 0.004 | 3 | Succinate-semialdehyde dehydrogenase | Cytoplasmic [Class 3] | Class 2 |
PA5554 | −2.0 | < 0.0001 | 15 | ATP synthase beta chain | Cytoplasmic [Class 3]; Outer Membrane Vesicle [Class 1] | Class 2 |
PA2259 | −2.1 | 0.006 | 1 | Transcriptional regulator PtxS | Cytoplasmic [Class 3] | Class 1 |
PA4317 | −2.2 | 0.006 | 1 | Hypothetical protein | Cytoplasmic Membrane [Class 3] | Class 4 |
PA4764 | −2.3 | 0.008 | 2 | Ferric uptake regulation protein | Cytoplasmic [Class 1]; Cytoplasmic [Class 3] | Class 1 |
PA1580 | −2.3 | 0.009 | 5 | Citrate synthase | Cytoplasmic [Class 3] | Class 1 |
PA4360 | −2.4 | 0.008 | 2 | Hypothetical protein | Unknown [Class 3]; Outer Membrane Vesicle [Class 1] | Class 4 |
PA1608 | −2.5 | 0.008 | 2 | Probable chemotaxis transducer | Cytoplasmic Membrane [Class 3]; Outer Membrane [Class 2] | Class 3 |
PA3214 | −2.7 | 0.002 | 2 | Hypothetical protein | Unknown [Class 3] | Class 4 |
PA0762 | −2.7 | 0.007 | 2 | Sigma factor AlgU | Cytoplasmic [Class 3] | Class 1 |
PA0122 | −2.8 | 0.003 | 4 | rahU | Extracellular [Class 3] | Class 1 |
PA4310 | −2.9 | 0.004 | 3 | Chemotactic transducer PctB | Cytoplasmic Membrane [Class 3] | Class 1 |
PA2654 | −3.2 | 0.008 | 6 | Probable chemotaxis transducer | Cytoplasmic Membrane [Class 3] | Class 3 |
PA2815 | −4.2 | 0.006 | 4 | Probable acyl-CoA dehydrogenase | Cytoplasmic Membrane [Class 3]; Outer Membrane Vesicle [Class 1] | Class 3 |
PA4876 | −4.7 | 0.003 | 2 | Osmotically inducible lipoprotein OsmE | Unknown [Class 3]; Outer Membrane Vesicle [Class 1] | Class 2 |
PA1324 | −6.1 | 0.003 | 5 | Hypothetical protein | Unknown [Class 3] | Class 4 |
PA3691 | −6.2 | 0.009 | 8 | Hypothetical protein | Unknown [Class 3]; Outer Membrane Vesicle [Class 1] | Class 4 |
PA3110 | −16.7 | < 0.0001 | 1 | Hypothetical protein | Unknown [Class 3] | Class 4 |
*Extracted from PGD. Class 1: Subcellular localization experimentally demonstrated in Pseudomonas aeruginosa. Class 2: Subcellular localization of a similar gene experimentally demonstrated in another organism OR to a paralog experimentally demonstrated in the same organism. BLAST expect value of 10e-10 for query within 80–120% of subject length. Class 3: Subcellular localization computationally predicted by PSORTb [44]. Bold indicates first time evidence of protein translation in PAO1