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. 2019 Apr 2;17:108. doi: 10.1186/s12967-019-1852-0

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Overexpression of ZCCHC13 promotes the G1-S transition and regulatory gene expressions in liver cancer cells. a Representative profiles of a flow cytometry analysis are shown in the left panel. b The percentages of cells in various phases of the cell cycle were calculated and presented as the mean ± SD from three experiments in the right panel (*p < 0.05, **p < 0.01). c Western blot analysis showing increased levels of the CDK1, CDK4 and c-MYC proteins and the phosphorylated AKT and ERK proteins following ZCCHC13 overexpression