Figure 1.

Leukotriene B4 (LTB4) levels in BAL fluid from patients with severe asthma and different granulocyte patterns. BAL was collected during bronchoscopy of individuals with severe treatment-resistant asthma, and enzyme immunoassays were run to measure LTB4 concentrations. Samples were analyzed based on BAL granulocyte patterns and LTB4 levels (presented as pg/ml). Data are presented as individual data points along with the mean ± SEM for each group. *P < 0.005 as compared with neutrophilic.