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. 2019 Apr 1;20:164. doi: 10.1186/s12859-019-2748-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — The components of the OncoTrack data coordination operation. The platform comprises three major components: the Electronic Data Capture System (EDC, OpenClinica), the Central Data Repository (OncoTrack DB), and the Data Integration System (tranSMART). The OpenClinica EDC system is used to collect medical history and observational patient data from clinical sites during the studies and feeds the structured data to the Central Data Repository. The Central Data Repository, OncoTrack DB is a sample indexed content management system. Data and results generated in the laboratories (before integration) are deposited and exchanged here. In order to link the different data types and layers, the data collected in the OncoTrack DB are integrated in the Data Integration System, tranSMART. The tranSMART data warehouse provides deep linking and integration between the clinical and laboratory data and a set of tools for the exploratory analysis of the integrated data