Incidence of hepatitis A in the United States. (A) Cases of acute hepatitis A per 100,000 population reported to the National Notifiable Diseases Surveillance System, United States, 1966–2013. (Panel from Murphy et al. 2016; reproduced courtesy of the Centers for Disease Control and Prevention © 2016.) (B) Incidence of hepatitis A virus by age group—United States, 2000–2015. (Source: CDC, National Notifiable Diseases Surveillance System, 2015.)