Table 4.
Hazard ratios for composite of ESRD or death associated with BUN and cSosm levels (sensitivity analysis)
| Analysis 1 | ||||
|---|---|---|---|---|
| HR | 95% CI | P | P for trend | |
| BUN | ||||
| Q1 | reference | < 0.01 | ||
| Q2 | 1.86 | 1.01–3.40 | 0.045 | |
| Q3 | 2.66 | 1.44–4.89 | < 0.01 | |
| Q4 | 3.11 | 1.50–6.46 | < 0.01 | |
| cSosm | ||||
| Q1 | reference | 0.42 | ||
| Q2 | 1.12 | 0.68–1.85 | 0.66 | |
| Q3 | 1.03 | 0.63–1.69 | 0.90 | |
| Q4 | 1.24 | 0.75–2.04 | 0.40 | |
Analysis 1: adjusted for age; sex; diabetes mellitus; smoking; systolic blood pressure; dyslipidemia; use of immunosuppressants, and diuretics; C-reactive protein; body mass index; daily proteinuria; hemoglobin; serum creatinine; serum phosphorus; and serum albumin
ESRD end-stage renal disease, BUN blood urea nitrogen, cSosm calculated serum osmolality, HR hazard ratio, CI confidence interval