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. 2019 Apr 2;16:7. doi: 10.1186/s12950-019-0211-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Portal venous atherosclerosis in human NAFLD. Two surgical specimens (I and II) were stained with hematoxylin and eosin (H&E) (a), trichrome (b), filipin (c), or an antibody against oxLDL (d). The portal venous plaque showed oxLDL and free cholesterol accumulation. The plaque caused the narrowing of the portal venous lumen (arrows, I) or was protruding and thus ruptured the vein (arrowheads, II). Scale bar: 100 μm