Table 2.

p-Values Resulting from Paired t-Tests

			Caudate node strength		ACC node strength		MFG node strength		PCC node strength		Caudate to MFG connection		PCC to MFG connection
Edge scheme	Clustering coefficient	Path length	L	R	L	R	L	R	L	R	L	R	L	R
B12	0.14	0.81	0.16	0.33	0.32	0.59	0.55	0.83	0.59	0.13	0.93	0.74	NA	NA
FA12	0.68	0.99	0.30	0.81	0.42	0.66	0.70	0.95	0.22	0.48	0.57	0.19	0.22	0.82
SC12	0.97	0.45	0.40	0.17	0.52	0.28	0.85	0.83	0.76	0.26	0.26	0.24	0.11	0.19
SDL12	0.84	0.80	0.35	0.25	0.41	0.40	0.89	0.95	0.55	0.43	0.35	0.31	0.11	0.19

The 12-week group's graph metrics were tested for differences using a paired t-test (two-tailed). Each row lists an edge scheme's results expressed as a p-value. (B, binary; FA, fractional anisotropy weight; SC, streamline count weight; SDL, streamline count with density and length correction weight), and top-most row denotes graph metrics. ACC, anterior cingulate cortex; L, left; PCC, posterior cingulate cortex; MFG, middle frontal gyrus; R, right. “NA”—PCC to MFG connections were not observed using the binary definition.