Table 6.
Results of Cross-Sectional Unadjusted and Adjusted Logistic Regression Analyses Examining Associations between Blood Pressure and Erectile Dysfunction §
| Unadjusted Model n=825 |
Adjusted Model n=789 |
|||
|---|---|---|---|---|
| Characteristic | Odds Ratio (95% CI) | P value | Odds Ratio (95% CI) | P value |
| Unadjusted Model | ||||
| Systolic Blood Pressure (per 5 mmHg increase) | 1.015 (1.00, 1.03) | 0.0109 | 1.005 (0.99, 1.02) | 0.46 |
| Diastolic Blood Pressure (per 5 mmHg increase) | 0.96 (0.95, 0.98) | <.0001 | 0.98 (0.96, 1.00) | 0.045 |
| Demographic Variables | ||||
| Age (yrs). | --- | --- | 1.055 (1.03, 1.08) | <.0001 |
| African-American vs. White | --- | --- | 1.01 (0.66, 1.55) | 0.97 |
| Hispanic vs. White | 1.10 (0.63, 1.90) | 0.75 | ||
| Other vs. White | --- | --- | 0.68 (0.21,2.23) | 0.52 |
| < High school vs. College Graduate | --- | --- | 2.14 (0.99, 4.66) | 0.055 |
| High School graduate/GED vs. College Graduate | --- | --- | 1.97 (1.15, 3.39) | 0.014 |
| Post High School vs. College Graduate | --- | --- | 1.25 (0.87, 1.81) | 0.23 |
| Lives with Others vs. Lives Alone | --- | --- | 1.004 (0.69, 1.47) | 0.99 |
| Behavioral Risk Factor and Medication Use Variables | ||||
| Pack-years of Smoking | --- | --- | 1.00 (0.99, 1.01) | 0.40 |
| Alcohol Consumption (drinks/typical wk) | --- | --- | 1.01 (0.92, 1.11) | 0.76 |
| Beta-blockers (BB) vs. no BB | --- | --- | 0.97 (0.68, 1.39) | 0.88 |
| Diuretics vs. No Diuretics | --- | --- | 0.93 (0.68, 1.29) | 0.67 |
| Calcium Channel Blockers vs.no Calcium Channel Blockers | --- | --- | 1.03 (0.74, 1.44) | 0.84 |
| Angiotensin Converting Enzyme (ACE) inhibitors vs. no ACE | 1.27 (0.90, 1.81) | 0.18 | ||
| Angiotensin Receptor Blockers (ARB) vs. no ARB | --- | --- | 0.97 (0.63, 1.52) | 0.91 |
| Any Cholesterol Medication | --- | --- | 0.84 (0.60, 1.18) | 0.31 |
| Any Phosphodiesterase type 5 Inhibitors | --- | --- | 0.95 (0.60, 1.50) | 0.82 |
| Cardiometabolic and Psychosocial Variables | ||||
| BMI (kg/m2) | --- | --- | 1.01 (0.99, 1.05) | 0.31 |
| eGFR (mL/min/1.73 m2) | --- | --- | 1.00 (0.99, 1.01) | 0.59 |
| MoCA Total Score a | --- | --- | 0.95 (0.90, 1.00) | 0.037 |
| PHQ-9 Total Score b | --- | --- | 1.10 (1.05, 1.16) | <.0001 |
| Number of Physical Comorbidities b | --- | --- | 1.07 (0.99. 1.16) | 0.08 |
§
defined as International Index of Erectile Function score ≥21 --- variable not included in model
a
Higher scores indicate better function
b
Higher scores indicate poorer function
significant (p<0.05) Adjusted Odds Ratios and 95% Confidence Intervals presented in bold