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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Breast Cancer Res Treat. 2018 Mar 6;170(1):55–67. doi: 10.1007/s10549-018-4738-6

Table 4.

Change in miRNA from baseline to end of the six-month intervention by arm in the LEAN triala,b

miRNA Usual care Intervention p value
hsa_miR_106b_5p 12.5 (2.3 to 22.7) −1.0 (−9.0 to 6.9) 0.041
hsa_miR_27a_3p −12 (−19 to −4.2) −2.6 (−8.4 to 3.2) 0.062
hsa_miR_191_5p −4.6 (−37 to 28.0) 32.1 (6.6 to 57.6) 0.082
hsa_let_7b_5p 19.8 (3.9 to 35.7) 2.5 (−9.9 to 14.9) 0.093
hsa_miR_92a_3p 32.3 (−23 to 87.3) −27 (−70 to 15.9) 0.094
hsa_miR_24_3p 6.7 (−13 to 26.2) 27.4 (12.2 to 42.7) 0.099

Abbreviations: LEAN: Lifestyle, Exercise and Nutrition, BMI: body mass index

a

Change in miRNA following intervention or usual care was controlled for baseline expression

b

p value <0.1 considered significant