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. 2017 Dec 18;3:17057. doi: 10.1038/micronano.2017.57

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Copyright © 2017 The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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In vivo spectra and IOP measurements. (a) A 2 s block of stacked resonance spectra from a 20 s remote optical detector measurement session performed at 10 Hz. The first spectra obtained at the start of the 2 s block are displayed at the top of the stack. The spectra recorded at subsequent times are sequentially stacked towards the bottom. (b) The IOP measurements before and after intravitreal injection of hypertonic saline to cause transient IOP elevation at 138 days after implantation. The sensor-derived IOPs (black symbol, n=20) and the TonoVet-derived IOPs (open blue circles, n=6) mirror each other and show a rise in IOP after injection followed by a gradual decline over the following 43–55 min. Error bars indicate standard deviations. (c) A comparison of IOP derived from sensor measurements vs TonoVet IOP measurements over a 138-day period.